Pathophysiology of prosthetic joint infection with formation of pus due to planktonic bacteria into the joint and formation of bacterial biofilm at the implant surface: Plantonik bacteria are bacteria in “optimal” environmental conditions to growth in the joint liquid, leading to recruitment of polymorphonuclear cells (PMNs), and formation of pus, composed by bacterial and PMNs remnants; Bacteria embedded in biofilm at the implant’s surface, that is inseparable from the implant surface, and tolerant to the immune system.