Table 1

Institutional protocol for VTE prophylaxis in patients undergoing THA based on risk stratification.

Risk stratification Regimen Duration
Low-risk patients (planned for fast-track or outpatient THA) Rivaroxaban 10 mg and aspirin 100 mg Rivaroxaban 10 mg once daily for 5 days starting on POD 1 plus aspirin 100 mg once daily for 30 days
Intermediate-risk patients (older than 60 years old, bilateral THA, diabetic, greater than Class I heart failure, atrial fibrillation, or varicose veins) Enoxaparin 40 mg + Dabigatran 220 mg/d (or 150 mg/d, adjusted for weight and renal function) Enoxaparin 40 mg starting on POD 1, dabigatran 220 mg/d (or 150 mg/d adjusted for weight and renal function) for 30 days commencing upon discharge [38]
High-risk patients (history of VTE, active cancer, greater than Class I congestive heart failure or atrial fibrillation treated with anticoagulant, thrombophilia, prolonged immobility, BMI >40, steroid administration, hip fracture) Enoxaparin 40 mg Enoxaparin 40 mg once daily starting on POD 1 for 30 days.

POD: Postoperative Day.

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