Table 4
Summary of key studies included in the manuscript.
| Study | Study type | Intervention | Sample size | Findings |
|---|---|---|---|---|
| Anderson, Dunbar, Murnaghan et al. Aspirin or Rivaroxaban for VTE Prophylaxis after Hip or Knee Arthroplasty. N Engl J Med (2018) | Randomised Controlled Trial | Rivaroxaban (10 mg once daily) for 14 days versus the “Wells Protocol” (rivaroxaban 10 mg once daily from up to and including POD 5, plus aspirin 81 mg once daily for 30 days starting on POD 6) | 3424 | Non-inferiority of the “Wells Protocol”. |
| No difference regarding bleeding events. | ||||
| Gonzalez A, Luime J, Uçkay I, Hannouche D, et al. Is There an Association Between Smoking Status and Prosthetic Joint Infection After Primary Total Joint Arthroplasty? J Arthroplasty (2018) | Registry-based cohort study | Pre-operative classification of smoking status into never, former, and current smoker. | 8559 | 1.8 fold increase in the risk of PJI in current and former smokers. |
| Incidence rates and hazard ratios (HR) for PJI for different smoking statuses assessed. | ||||
| Gibbs VN, McCulloch RA, Dhiman P, et al. Modifiable risk factors for mortality in revision total hip arthroplasty for periprosthetic fracture. Bone Jt J (2020) | Retrospective cohort study | Univariate and multivariate logistic regression analyses to identify modifiable factors associated with 90-day and one year mortality in patients undergoing revision THA for periprosthetic hip fracture | 203 | Dislocation and hospital-acquired pneumonia identified as potentially modifiable risk factors. |
| Thien T, Chatziagorou G, Garellick G et al. Periprosthetic femoral fracture within two years after total hip replacement: analysis of 437,629 operations in the nordic arthroplasty register association database. J Bone Joint Surg Am (2014) | Registry study (Nordic Arthroplasty Register Association database) | Studied seven frequently used stems from 1995 to 2009; two cemented [Exeter and Lubinus SP II] and five uncemented [Bi-Metric, Corail, CLS Spotorno, ABG I, and ABG II]) | 437,629 | 2-year incidence of revision 0.47% for uncemented stems and 0.07% for cemented stems. |
| Revision increased with age in the uncemented group. | ||||
| HR for Exeter stem five times higher than Lubinus SP II stem | ||||
| Uncemented stems – ABG II stem increased HR (1.63) | ||||
| Corail stem decreased HR (0.47) | ||||
| Vigdorchik J, Jerabek SA, Mayman DJ et al. Evaluation of the spine is critical in the workup of recurrent instability after total hip arthroplasty. Bone Jt J (2019) | Prospective, matched cohort study | Pre-operative imaging – supine and standing AP pelvis and lateral radiographs in patients undergoing revision THA for recurrent instability | 222 | Utilisation of Hip-Spine Classification System in revision THA resulted in 97% patients having 2-year survival free of dislocation versus 84% without imaging. |
| Kayani B, Konan S, Thakrar RR et al. Assuring the long-term total joint arthroplasty. Bone Joint J (2019) | Prospective cohort study | Compare accuracy in restoration of native centre of rotation in conventional versus robotic THA | 75 | Robotic THA associated with improved restoration of rotation centre and combined offset. |
| More accurate positioning of the acetabular cup within the safe zones with robotic THA. |
POD: Post-operative day, PJI: Prosthetic joint infection, HR: Hazard Ratio, AP: anteroposterior, THA: Total Hip Arthroplasty.
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