Open Access
Table A.6.
Subgroup analysis by BMI.
| Follow up visit | Mean value and comparison within time period |
Comparison by time within subgroups (Bonferroni adjusted p-value) |
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|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BMI < 27 |
BMI ≥ 27 |
BMI < 27 |
BMI ≥ 27 |
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| Unadjusted mean ± SD (n) | Unadjusted mean ± SD (n) | p-value | Preop | 6 Month | 1 Year | 2 Year | 3 Year | Preop | 6 Month | 1 Year | 2 Year | 3 Year | |
| UCLA | |||||||||||||
| Preop | 3.9 ± 1.6 (113) | 3.8 ± 1.6 (109) | 0.4800 | – | – | – | – | – | – | – | – | – | – |
| 6 Month | 3.5 ± 1.4 (101) | 5.5 ± 1.4 (94) | 0.9481 | <.0001* | – | – | – | – | <.0001* | – | – | – | – |
| 1 Year | 6.1 ± 1.6 (86) | 5.7 ± 1.6 (92) | 0.0531 | <.0001* | 0.0054* | – | – | – | <.0001* | 1.0000 | – | – | – |
| 2 Year | 6.4 ± 1.6 (73) | 5.8 ± 1.5 (72) | 0.0078* | <.0001* | <.0001* | 1.0000 | – | – | <.0001* | 1.0000 | 1.0000 | – | – |
| 3 Year | 6.4 ± 1.6 (71) | 6.0 ± 1.5 (72) | 0.0876 | <.0001* | <.0001* | 1.0000 | 1.0000 | – | <.0001* | 1.0000 | 1.0000 | 1.0000 | – |
| 5 Year | 6.7 ± 1.3 (42) | 6.1 ± 1.5 (34) | 0.0895 | <.0001* | 0.0020* | 1.0000 | 1.0000 | 1.0000 | <.0001* | 1.0000 | 1.0000 | 1.0000 | 1.0000 |
| EQ5D | |||||||||||||
| Preop | 0.5 ± 0.3 (113) | 0.4 ± 0.3 (109) | 0.3586 | – | – | – | – | – | – | – | – | – | – |
| 6 Month | 0.9 ± 0.2 (101) | 0.9 ± 0.2 (92) | 0.3175 | <.0001* | – | – | – | – | <.0001* | – | – | – | – |
| 1 Year | 0.9 ± 0.2 (86) | 0.9 ± 0.2 (90) | 0.2969 | <.0001* | 0.0872 | – | – | – | <.0001* | 1.0000 | – | – | – |
| 2 Year | 0.9 ± 0.2 (72) | 0.9 ± 0.2 (72) | 0.2811 | <.0001* | 0.1004 | 1.0000 | – | – | <.0001* | 1.0000 | 1.0000 | – | – |
| 3 Year | 0.9 ± 0.2 (71) | 0.9 ± 0.2 (72) | 0.1534 | <.0001* | 1.0000 | 1.0000 | 1.0000 | – | <.0001* | 1.0000 | 1.0000 | 1.0000 | – |
| 5 Year | 1.0 ± 0.1 (39) | 0.9 ± 0.1 (34) | 0.1259 | <.0001* | <.0001* | 1.0000 | 0.3516 | 1.0000 | <.0001* | 0.3336 | 1.0000 | 1.0000 | 1.0000 |
| HHS | |||||||||||||
| Preop | 50.3 ± 12.2 (113) | 48.7 ± 13.5 (109) | 0.2623 | – | – | – | – | – | – | – | – | – | – |
| 6 Month | 93.0 ± 9.8 (100) | 94.6 ± 7.7 (94) | 0.2602 | <.0001* | – | – | – | – | <.0001* | – | – | – | – |
| 1 Year | 96.1 ± 7.7 (85) | 96.6 ± 5.5 (92) | 0.8948 | <.0001* | <.0001* | – | – | – | <.0001* | 0.0418* | – | – | – |
| 2 Year | 96.5 ± 7.8 (72) | 96.1 ± 6.5 (72) | 0.1446 | <.0001* | <.0001* | 0.2509 | – | – | <.0001* | 0.0833 | 1.0000 | – | – |
| 3 Year | 96.2 ± 8.3 (71) | 97.6 ± 5.7 (71) | 0.29 | <.0001* | 0.0003* | 1.0000 | 1.0000 | – | <.0001* | 0.0106* | 0.9757 | 0.2402 | – |
| 5 Year | 98.4 ± 2.9 (39) | 96.1 ± 5.9 (34) | 0.0733 | <.0001* | <.0001* | 0.2266 | 0.3864 | 1.0000 | <.0001* | 0.0175* | 1.0000 | 1.0000 | 1.0000 |
| Oxford | |||||||||||||
| Preop | 22.2 ± 7.4 (113) | 21.9 ± 7.9 (109) | 0.8968 | – | – | – | – | – | – | – | – | – | – |
| 6 Month | 43.8 ± 5.4 (101) | 42.9 ± 5.5 (94) | 0.1147 | <.0001* | – | – | – | – | <.0001* | – | – | – | – |
| 1 Year | 45.0 ± 5.4 (86) | 44.6 ± 4.3 (92) | 0.0776 | <.0001* | 0.0180* | – | – | – | <.0001* | 0.0153* | – | – | – |
| 2 Year | 45.5 ± 4.6 (73) | 45.2 ± 3.9 (72) | 0.1347 | <.0001* | 0.0001* | 1.0000 | – | – | <.0001* | 0.0039* | 0.4147 | – | – |
| 3 Year | 45.7 ± 4.8 (71) | 45.9 ± 3.2 (71) | 0.1796 | <.0001* | 0.0024* | 1.0000 | 1.0000 | – | <.0001* | 0.0003* | 0.0871 | 1.0000 | – |
| 5 Year | 46.8 ± 1.9 (42) | 46.0 ± 3.3 (34) | 0.2548 | <.0001* | <.0001* | 0.4758 | 1.0000 | 1.0000 | <.0001* | <.0001* | 1.0000 | 1.0000 | 1.0000 |
| Aluminum (μg/L) | |||||||||||||
| Preop | 12.3 ± 1.9 (21) | 11.6 ± 1.7 (10) | 0.183 | – | – | – | – | – | – | – | – | – | – |
| 6 Month | 12.3 ± 1.8 (16) | 11.9 ± 1.8 (9) | 0.5903 | 1.0000 | – | – | – | – | 1.0000 | – | – | – | – |
| 1 Year | 13.9 ± 3.2 (13) | 14.5 ± 4.2 (11) | 0.7495 | 1.0000 | 1.0000 | – | – | – | 0.8438 | 1.0000 | – | – | – |
| 2 Year | 13.3 ± 2.0 (12) | 14.4 ± 5.3 (9) | 0.2267 | 1.0000 | 1.0000 | 1.0000 | – | – | 1.0000 | 1.0000 | 1.0000 | – | – |
| 5 Year | 14.7 ± 3.1 (4) | 13.4 ± 1.5 (3) | 0.2888 | 1.0000 | 1.0000 | 1.0000 | – | 1.0000 | 1.0000 | 1.0000 | 1.0000 | – | 1.0000 |
| Titanium (μg/L) | |||||||||||||
| Preop | 2.1 ± 0.6 (4) | 1.2 ± 0.9 (5) | 0.6242 | – | – | – | – | – | – | – | – | – | – |
| 6 Month | 2.1 ± 1.3 (29) | 2.4 ± 2.3 (14) | 0.1859 | 1.0000 | – | – | – | – | 1.0000 | – | – | – | – |
| 1 Year | 2.0 ± 1.1 (20) | 2.4 ± 2.3 (15) | 0.137 | 1.0000 | 1.0000 | – | – | – | 1.0000 | 1.0000 | – | – | – |
| 2 Year | 2.2 ± 0.8 (15) | 2.4 ± 3.4 (12) | 0.0667 | 1.0000 | 1.0000 | 1.0000 | – | – | 1.0000 | 1.0000 | 1.0000 | – | – |
| 5 Year | 1.3 ± 1.3 (3) | 1.2 ± 0.2 (2) | 1.0000 | 1.0000 | 1.0000 | 1.0000 | – | 1.0000 | 1.0000 | 1.0000 | 1.0000 | – | 1.0000 |
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