Open Access
Table 1
Univariate Cox regression analysis of local recurrence-free survival in patients who had localized mesenchymal chondrosarcoma and underwent surgery or CIRT.
| Variable (n = 49) | No. of patients | Hazard ratio (95% CI) | p-value |
|---|---|---|---|
| Age (years) | 49 | 1.01 (0.97–1.05) | 0.626 |
| Sex | |||
| Male | 26 | 1 | |
| Female | 23 | 0.36 (0.07–1.86) | 0.223 |
| Year of diagnosis | |||
| 2006 to 2013 | 17 | 1 | |
| 2014 to 2022 | 32 | 6.39 (0.75–54.75) | 0.091 |
| Previous surgery | |||
| No | 42 | 1 | |
| Yes | 7 | 3.49 (0.78–15.66) | 0.103 |
| Tissue of origin | |||
| Skeletal | 26 | 1 | |
| Extra-skeletal | 23 | 1.60 (0.36–7.16) | 0.539 |
| Site | |||
| Head and neck | 5 | 1 | |
| Trunk | 27 | 0.35 (0.06–1.94) | 0.230 |
| Limbs | 17 | 0.15 (0.01–1.63) | 0.118 |
| Tumor size (cm) | 49 | 0.98 (0.79–1.22) | 0.861 |
| Surgical margin | |||
| R0 | 38 | 1 | |
| R1 or R2 | 4 | 17.44 (2.17–139.98) | 0.007* |
| CIRT | 7 | 1.96 (0.21–17.89) | 0.550 |
| Adjuvant radiotherapy | |||
| No | 45 | 1 | |
| Yes | 4 | 5.18 (0.99–27.12) | 0.051 |
| Adjuvant chemotherapy | |||
| No | 27 | 1 | |
| Yes | 22 | 1.57 (0.35–7.01) | 0.557 |
*Statistically significant. CI, confidence interval; CIRT, carbon ion radiotherapy.
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