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Table 2
Univariate Cox regression analysis of distant metastasis-free survival in patients with localized mesenchymal chondrosarcoma
| Variable (n = 57) | No. of patients | Hazard ratio (95% CI) | p-value |
|---|---|---|---|
| Age (years) | 57 | 1.00 (0.98–1.02) | 0.861 |
| Sex | |||
| Male | 30 | 1 | |
| Female | 27 | 0.45 (0.19–1.06) | 0.067 |
| Year of diagnosis | |||
| 2006 to 2013 | 19 | 1 | |
| 2014 to 2022 | 38 | 0.84 (0.36–1.96) | 0.692 |
| Previous surgery | |||
| No | 48 | 1 | |
| Yes | 9 | 1.67 (0.61–4.53) | 0.317 |
| Tissue of origin | |||
| Skeletal | 31 | 1 | |
| Extra-skeletal | 26 | 0.63 (0.26–1.51) | 0.299 |
| Site | |||
| Head and neck | 6 | 1 | |
| Trunk | 33 | 1.40 (0.31–6.28) | 0.663 |
| Limbs | 18 | 2.03 (0.43–9.63) | 0.374 |
| Tumor size (cm) | 57 | 1.14 (1.04–1.26) | 0.007* |
| Surgical margin | |||
| R0 | 38 | 1 | |
| R1 or R2 | 4 | 1.47 (0.34–6.46) | 0.609 |
| CIRT | 7 | 0.77 (0.23–2.64) | 0.680 |
| No surgery | 8 | 0 | 0.999 |
| Adjuvant radiotherapy | |||
| No | 53 | 1 | |
| Yes | 4 | 0.71 (0.10–5.35) | 0.741 |
| Adjuvant chemotherapy | |||
| No | 33 | 1 | |
| Yes | 24 | 1.76 (0.75–4.09) | 0.192 |
*Statistically significant. CI, confidence interval; CIRT, carbon ion radiotherapy.
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