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Table 3
Univariate Cox regression analysis of disease-specific survival in patients with localized mesenchymal chondrosarcoma.
| Variable (n = 57) | No. of patients | Hazard ratio (95% CI) | p-value |
|---|---|---|---|
| Age (years) | 57 | 1.03 (1.00–1.06) | 0.085 |
| Sex | |||
| Male | 30 | 1 | |
| Female | 27 | 0.35 (0.09–1.34) | 0.125 |
| Year of diagnosis | |||
| 2006 to 2013 | 19 | 1 | |
| 2014 to 2022 | 38 | 2.41 (0.51–11.50) | 0.269 |
| Previous surgery | |||
| No | 48 | 1 | |
| Yes | 9 | 1.82 (0.36–9.13) | 0.465 |
| Tissue of origin | |||
| Skeletal | 31 | 1 | |
| Extra-skeletal | 26 | 0.80 (0.22–2.85) | 0.726 |
| Site | |||
| Head and neck | 6 | 1 | |
| Trunk | 33 | 0.45 (0.09–2.37) | 0.345 |
| Limbs | 18 | 0.11 (0.01–1.33) | 0.083 |
| Tumor size (cm) | 57 | 1.04 (0.88–1.23) | 0.647 |
| Surgical margin | |||
| R0 | 38 | 1 | |
| R1 or R2 | 4 | 17.42 (2.18–138.90) | 0.007* |
| CIRT | 7 | 3.14 (0.56–17.71) | 0.196 |
| No surgery | 8 | 1.74 (0.20–14.95) | 0.615 |
| Adjuvant radiotherapy | |||
| No | 53 | 1 | |
| Yes | 4 | 4.65 (0.48–45.16) | 0.186 |
| Adjuvant chemotherapy | |||
| No | 33 | 1 | |
| Yes | 24 | 0.99 (0.28–3.47) | 0.990 |
*Statistically significant. CI, confidence interval; CIRT, carbon ion radiotherapy.
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