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Table 2

Cox regression analysis of local recurrence-free survival in the patients who had localized dedifferentiated chondrosarcoma and received surgery.

Univariate analysis
Variable (n = 84) No. of patients Hazard ratio (95% CI) P value
Age (years) 84 0.99 (0.96–1.02) 0.554
Sex
 Male 49 1
 Female 35 1.35 (0.56–3.25) 0.499
Previous surgery, n (%)
 No 79 1
 Yes 5 1.95 (0.45–8.43) 0.371
Site
 Trunk 31 1
 Upper limb 17 0.30 (0.06–1.35) 0.117
 Lower limb 36 0.58 (0.23–1.47) 0.247
Tumor size (cm) 84 0.95 (0.85–1.05) 0.338
Surgical margin
 R0 70 1
 R1 or R2 14 3.39 (1.35–8.52) 0.010*
Adjuvant radiotherapy
 No 73 1
 Yes 11 2.41 (0.87–6.64) 0.090
Adjuvant chemotherapy
 No 67 1
 Yes
17
0.75 (0.25–2.24)
0.605
Multivariate analysis
Variable
No. of patients
Hazard ratio (95% CI)
P value
Surgical margin
 R0 70 1
 R1 or R2 14 3.39 (1.35–8.52) 0.010*
*

Statistically significant.

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