Issue |
SICOT-J
Volume 9, 2023
|
|
---|---|---|
Article Number | 30 | |
Number of page(s) | 6 | |
Section | Hip | |
DOI | https://doi.org/10.1051/sicotj/2023029 | |
Published online | 30 October 2023 |
Original Article
Can nutritional and inflammatory indices predict 90-day mortality in fragility hip fracture patients?
1
Department of Orthopaedic Surgery, Rabin Medical Center, 39 Jabotinsky st., Petach Tikva 4941492, Israel
2
Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv, Tel Aviv 6423906, Israel
3
Beit Rivka Geriatric Rehabilitation Center, 4 Ha Hamisha st., Petach Tikva 4924577, Israel and Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv, Tel Aviv 6423906, Israel
4
Department of Orthopaedic Surgery, Samson Assuta Ashdod University Hospital and Faculty of Health Sciences, Ben Gurion University, 7, Ha’Refua Street, 7747629 Ashdod, Israel
* Corresponding author: shaishe@bgu.ac.il
Received:
13
July
2023
Accepted:
22
September
2023
Introduction: Hip fractures in the elderly are related to increased mortality. The identification of patients at risk is essential. Several nutritional and inflammatory parameters were investigated in an effort to find a prognostic indicator for mortality following fragility hip fractures (FHF) surgery. We aim to evaluate their utility and compare between the different factors. Methods: A retrospective cohort study of patients 65 years and older, who underwent surgery following fragility hip fractures between January 2012 and June 2020, was conducted. Patients who died within 90 days were matched at a 1:1 ratio with surviving controls, based on age, gender, fracture type, and comorbidities. Nutritional and inflammatory indices, including serum albumin, protein energy malnutrition (PEM), albumin-to-globulin ratio (AGR), prognostic nutritional index (PNI), the systemic immune-inflammation index (SII), platelet-to-lymphocyte ratio (PLR), and the neutrophile-to-lymphocyte ratio (NLR), were compared between groups. Results: 304 patients were included, 152 in each group. Patients’ demographics were similar. Among all indices evaluated, only the PLR significantly differed between the study groups (236.9 ± 193.5 for the study group vs. 186.6 ± 119.3 for the control group (p = 0.007). In patients who survived the initial hospitalization, the PEM was also found to be correlated with 90 days mortality. Discussion: The PLR was found to be correlated with mortality risk following FHF surgery. As it can be easily calculated from accessible blood tests, we recommend its’ routine assessment as a screening tool for personalized management of patients at high risk for mortality.
Key words: Fragility hip fracture / Survival / Nutrition / Inflammation / Platelet-to-lymphocyte ratio
© The Authors, published by EDP Sciences, 2023
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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