Table 1.

Summary of studies assessing the efficiency of BMAC in the management of rotator cuff tears.

Study ID Design Population Intervention Comparator Outcome measure Findings
Ellera Gomes et al. [41] Single arm prospective study Fourteen patients (nine women, five men) with full thickness rotator cuff tears Trans-osseous stitches augmented with BMAC utilizing a mini-open technique No control University of California Los Angeles From 12 ± 3.0 to 31 ± 3.2
Tendon integrity (12 months) Tendon integrity was maintained in 100% of cases.
Hernigou et al. [20] Prospective, matched-control, study Fifty-four patients BMAC in augmenting arthroscopic single row rotator cuff repair Matched control group of 45 patients without augmentation with BMAC Tendon integrity (six months) 100% vs. 67%
Tendon integrity (10 years) 87% vs. 44%
Centeno et al. [44] Prospective multicentre cohort study Patients with osteoarthritis with and without rotator cuff pathology BMAC injection for the gleno-humeral OA None
  • The arm, shoulder and hand score

  • Visual analogue score

  • Mean subjective improvement

  • Improved from 36.1 to 17.1 (P < 0.001)

  • Improved from 4.3 to 2.4 (P < 0.001)

  • 48.8%

Havlas et al. [43] Prospective, matched-control, study Forty-five patients BMAC in augmenting arthroscopic single row rotator cuff repair Matched control group of 45 patients without augmentation with BMAC Tendon integrity (6 months) (100%) compared to 30 (67%)

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