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Table 1

Patient characteristics.

Baseline characteristics The total cohort No persistent pain Persistent pain p-value
n = 119 n = 65 n = 22
Age in years, mean (SD) 56 (10.4) 59 (10.2) 54 (8.8) 0.04
Gender, n (% of total)
 Female 61 (51.3) 33 (50.8) 14 (63.6) 0.30
BMI (kg/m2), mean (SD) 26.8 (4.3) 27 (4.1) 28 (5.9) 0.56
 Missing 5 0 0
Level of education, n (% of total)
 Low level of education 91 (76.5) 38 (58.5) 17 (77.3) 0.29
 High level of education 27 (22.7) 27 (41.5) 5 (22.7)
 Missing 1 (0.8) 0 0
Marital status, n (% of total)
 Single/widowed 95 (79.8) 10 (15.4) 4 (18.2) 0.76
 Cohabitants/married 23 (19.3) 55 (84.6) 18 (81.8)
 Missing 1 (0.8) 0 0
Employment, n (% of total)
 No 23 (19.3) 7 (10.8) 10 (45.5) <0.01
 Yes 66 (55.5) 36 (55.4) 9 (40.9)
 Retired 25 (21.0) 20 (30.8) 3 (13.6)
 Missing 5 (4.2) 2 (3.1) 0
Insurance case, n (% of total)
 Missing 14 (11.8) 2 (3.1) 7 (31.8) <0.01
 Pain elsewhere 1 (0.8) 0 0
 No 33 (27.7) 17 (26.2) 2 (9.1) 0.09
 Yes 85 (71.2) 48 (73.8) 20 (90.1)
 Missing 1 (0.8) 0 0
Shoulder-specific parameters
 WORC, mean (SD) 1284 (402) 1227 (392) 1455 (285) 0.01
 SANE, mean (SD) 51 (18.4) 51 (19.1) 48.5 (13.9) 0.53
 Worst pain, median [range] 7 [0–10] 7 [0–10] 7 [3–10] 0.29
 24 h average pain, median [range] 5 [0–10] 5 [0–10] 5 [2–8] 0.67
Type of surgery, n (% of total)
 ASD 43 (36.1) 25 (38.5) 8 (36.4) 0.03
 AC resection 20 (16.8) 6 (9.2) 7 (31.8)
 ASD and AC resection 56 (47.1) 34 (52.3) 7 (31.8)
Expected outcome after surgery
Average pain median [range] 7 [0–10] 7 [1–10] 7.5 [3–10] 0.26
Return to work/daily living, n (% of total)
 <4 weeks 41 (34.5) 23 (35.4) 9 (40.9) 0.68
 1–2 months 40 (33.6) 28 (43.1) 4 (18.2)
 3–4 months 29 (24.4) 10 (15.4) 8 (36.4)
 5–6 months 3 (2.5) 1 (1.5) 0
 >6 months 2 (1.7) 1 (1.5) 0
 Missing 4 (3.4) 2 (3.1) 1 (4.5)
Conditioned pain modulation
 PPT shoulder, mean (SD) 272 (140) 273 (140) 290 (110) 0.65
 PPT thigh, mean (SD) 477 (226) 455 (217) 530 (207) 0.18
 CPM shoulder, n (%)
  Inefficient 13 (10.9) 7 (10.8) 1 (4.5) 0.33
  Efficient 79 (66.4) 45 (69.2) 18 (81.8)
  Missing 27 (22.7) 13 (20.0) 3 (13.6)
 CPM thigh, n (%)
  Inefficient 9 (7.6) 6 (9.2) 0 0.33
  Efficient 80 (67.2) 45 (69.2) 17 (77.3)
  Missing 30 (25.2) 14 (21.5) 5 (22.7)
Psychological parameters
 PCS total, n (%)
  Low risk 67 (56.3) 37 (56.9) 11 (50) 0.69
  Moderate risk 31 (26.1) 18 (27.7) 8 (26.4)
  High risk 21 (17.6) 10 (15.4) 3 (13.6)
 HADS-a, n (%)
  Low risk 97 (81.5) 54 (83.1) 17 (77.3) 0.06
  Moderate risk 13 (10.9) 6 (9.2) 3 (13.6)
  High risk 9 (7.6) 5 (7.7) 2 (9.1)
 HADS-d, n (%)
  Low risk 105 (88.2) 57 (87.7) 19 (86.4) 0.13
  Moderate risk 8 (6.7) 5 (7.7) 1 (4.5)
  High risk 6 (5.0) 3 (4.6) 2 (9.1)
 s-STAI, n (%)
  Low risk 83 (69.7) 47 (72.3) 12 (54.5) 0.12
  High risk 36 (30.3) 18 (27.7) 10 (45.5)
 t-STAI, n (%)
  Low risk 89 (74.8) 53 (81.5) 11 (50.0) <0.01
  High risk 30 (25.2) 12 (18.5) 11 (50.0)

BMI, body mass index; WORC, Western Ontario Rotator Cuff Index; SANE, Single Assessment Numeric Evaluation; ASD, arthroscopic subacromial decompression; AC resection, acromioclavicular joint resection; CPM, conditioned pain modulation STAI, State-Trait Anxiety FORM Y; HADS, Hospital Anxiety and Depression Scale; PCS, Pain Catastrophizing Scale.

Separate characteristics for patients with shoulder pathology (n = 10) and the four patients who declined to have a follow-up examination 6 months after surgery are not shown. The 18 non-responders had undergone ASD (n = 4), AC resection (n = 4) and ASD with AC resection (n = 10) and were significantly younger (p = 0.03), but did not differ in regard to gender, psychological characteristics, or conditioned pain modulation response. A patient was considered to have an efficient endogenous pain modulation capacity if the test pain was reduced during cold water immersion.

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