Aggressive tumors such as this synovial-cell sarcoma, stage G3T2bN1M1, require very invasive surgery and a customized reconstructive solution (in this case radical forequarter amputation with chest wall resection with a myocutaneous latissimus dorsi flap was planned). Neoadjuvant therapy was scheduled prior to surgery, however, the patient succumbed to the disease secondary to pulmonary metastases.