Table 2.

Factors influencing the choice of immediate-definitive extremity reconstruction.

Established diagnosis
Histological certainty about margins
Feasibility of performing major reconstruction at time of resection without high risk factors (i.e. anesthesia, infection, bleeding disorders, etc.)
Feasibility of conducting the procedure as a single-stage procedure
Absence of non-oncologic conditions contraindicating immediate reconstruction (e.g., infection)
Defect repair does not impair physical examination/surveillance
Completion of neoadjuvant treatment (if applicable)
Feasibility of completion of definitive reconstruction without delaying adjuvant treatment (if applicable)
Feasibility of combining reconstruction with adjuvant therapy if applicable (e.g. brachytherapy)
Primary size of tumor <5 cm
Patient age <50 years
Low tumor grading
New tumor recurrence
No presence/evidence of metastases

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