Factors influencing the choice of immediate-definitive extremity reconstruction.
|Histological certainty about margins|
|Feasibility of performing major reconstruction at time of resection without high risk factors (i.e. anesthesia, infection, bleeding disorders, etc.)|
|Feasibility of conducting the procedure as a single-stage procedure|
|Absence of non-oncologic conditions contraindicating immediate reconstruction (e.g., infection)|
|Defect repair does not impair physical examination/surveillance|
|Completion of neoadjuvant treatment (if applicable)|
|Feasibility of completion of definitive reconstruction without delaying adjuvant treatment (if applicable)|
|Feasibility of combining reconstruction with adjuvant therapy if applicable (e.g. brachytherapy)|
|Primary size of tumor <5 cm|
|Patient age <50 years|
|Low tumor grading|
|New tumor recurrence|
|No presence/evidence of metastases|
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