Issue |
SICOT-J
Volume 7, 2021
|
|
---|---|---|
Article Number | 35 | |
Number of page(s) | 5 | |
Section | Knee | |
DOI | https://doi.org/10.1051/sicotj/2021034 | |
Published online | 19 May 2021 |
Original Article
Stiffness after unicompartmental knee arthroplasty: Risk factors and arthroscopic treatment
1
Department of Orthopedic Surgery and Sport Medicine, Croix-Rousse Hospital, FIFA Medical Center of Excellence, 69004 Lyon, France
2
Univ Lyon, Université Claude Bernard Lyon 1, IFSTTAR, LBMC UMR_T9406, 69622 Lyon, France
3
EA 7424 – Interuniversity Laboratory of Human Movement Science, Université Lyon 1, Lyon, France
* Corresponding author: gaspard.fournier@chu-lyon.fr
Received:
8
January
2021
Accepted:
8
March
2021
Introduction: One of the principal complications after total knee arthroplasty (TKA) is stiffness. There are no publications concerning stiffness after unicompartmental knee arthroplasty (UKA). Study objectives were to describe the incidence of stiffness after UKA, to look for risk factors, and to describe safe and effective arthroscopic treatment. Methods: There were 240 UKA performed between March 2016 and January 2019 included. Robotic-assisted surgery was performed in 164 patients and mechanical instrumentation in 76 patients. Stiffness was defined as flexion < 90° or a flexion contracture > 10° during the first 45 post-operative days. Patients with stiffness were treated with arthroscopic arthrolysis. Several factors were studied to look for risk factors of stiffness: body mass index, gender, age, mechanical or robotic instrumentation, preoperative flexion, previous meniscectomy, and anticoagulant treatment. Arthrolysis effectiveness was evaluated by flexion improvement and UKA revision rate. Results: 22 patients (9%) developed stiffness. Mechanical instrumentation significantly increased the risk of stiffness with OR = 0.26 and p = 0.005. Robotic-assisted surgery decreased the risk of stiffness by five-fold. Before arthrolysis, mean knee flexion was 79°, versus 121° (53% improvement) after arthroscopic arthrolysis. Only 2 patients (9%) underwent UKA revision after arthrolysis. Discussion: Stiffness after UKA is an important complication with an incidence of 9% in this study. Arthroscopic arthrolysis is a safe and effective treatment with a range of motion improvement of > 50%. Robotic-assisted surgery significantly decreases the risk of postoperative stiffness.
Level of evidence: Level III, therapeutic study, retrospective cohort study
Key words: Unicompartmental Knee Arthroplasty / UKA / Stiffness / Arthroscopic treatment / Arthrolysis
© The Authors, published by EDP Sciences, 2021
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Introduction
Unicompartmental knee arthroplasty (UKA) is a common treatment for partial knee osteoarthritis. Outcomes of UKA have improved in recent years, likely due to improved surgical technique and superior implant designs. Performing UKA with robotic assistance results in better implant positioning and decreased complications [1, 2]. Numerous publications are showing that UKA has a decreased complication rate and superior postoperative results compared to total knee arthroplasty (TKA) [3–8]. Complications of UKA include osteoarthritis progression, aseptic loosening, bearing dislocation, and pain [9, 10]. For these complications, the recommended treatment is a revision to TKA, which is a difficult surgery. This may explain why some surgeons prefer to primarily perform TKA.
Stiffness is a common complication of TKA, with a reported incidence of between 1% and 13% postoperatively [11, 12]; treatments performed include manipulation under anesthesia, arthrolysis arthroscopically or open, and revision TKA. Stiffness after TKA is defined as flexion < 90° or a flexion contracture > 10° (lack of extension). We define early stiffness at < 45 days post-TKA, late stiffness < 6 months postoperatively, and chronic stiffness that lasts for > 6 months.
Stiffness is not frequently reported in UKA. Only a few studies report this complication [13, 14], and there is no literature on stiffness and risk factors after UKA. The objectives of this study were to report the incidence of stiffness after UKA, in the first three postoperative months, then, to investigate risk factors for stiffness, and finally to describe and analyze arthroscopic treatment and its effectiveness.
Hypothesis was that robotic instrumentation decrease the rate of stiffness versus mechanical instrumentation and that arthroscopic debridement is a safe and efficient treatment of stiffness after UKA.
Materials and methods
Population
This single-centre retrospective study was based on prospectively collected data of a cohort of 240 consecutive primary UKAs performed at our department between March 2016 and January 2019 by two senior surgeons. Inclusion criteria were all patients who underwent a UKA in that study period with a minimum follow-up of 1 year.
Exclusion criteria were patients with previous knee fracture, previous osteotomy, anterior cruciate ligament reconstruction, or sagittal instability before surgery to decrease the risk of UKA failure (Figure 1). Characteristics of the final population of 240 patients are summarized in Table 1.
Figure 1 Flowchart. |
Final study population characteristics SD standard deviation, Min minimum, Max maximum.
Ethical considerations
All procedures were performed by the ethical standards of the institutional and/or national research committee, the 1964 Helsinki declaration, and its later amendments, or comparable ethical standards.
Operative technique
The medial mid-vastus approach was systematically used for medial UKA and the lateral parapatellar approach was used for lateral UKA. Two different implants were used, and two different instrumentations were used: mechanical instrumentation or robot-assisted surgery. The first type of implant used was a cemented resurfacing unicompartmental prosthesis with an all-polyethylene tibial component (HLS Uni Evolution™, Corin®) (Figure 2).
Figure 2 Medial HLS Uni Evolution™ UKA (AP view and profile). |
The second type of implant used was a cemented resurfacing unicompartmental prosthesis with a metal-backed tibial component (Journey™ Uni unicompartmental knee system, Smith and Nephew®) (Figure 3).
Figure 3 Medial Journey™ UKA, (AP view and profile). |
The BlueBelt Navio robotic surgical system (Smith and Nephew®) was used in robotic-assisted surgery [15]. The surgical robotic-assisted or conventional techniques have already been described [16]. The distribution of the two different implants among the study population is shown in Table 2.
Distribution of implants and surgical technique.
Follow-up and evaluation
Patients underwent clinical and radiological evaluation at 21 days, 45 days, 3 months, 1 year postoperatively, and then every year thereafter. The initial diagnosis of stiffness was made clinically during the first 45 days postoperatively. Radiographic examination was performed at each consultation (including weight-bearing anteroposterior and lateral knee radiographs, patellar axial view, and full-length standing radiographs).
Arthroscopic treatment of stiffness
The treatment of stiffness consisted of arthroscopic arthrolysis. Two standard anterior portals were made: inferolateral and inferomedial, and only if necessary, a third superolateral portal was made. A step-by-step approach was used as described by Volchenko et al. [17] for TKA arthroscopic arthrolysis. The first step was debridement of the patellofemoral and suprapatellar compartments. Then, medial and lateral gutter synovectomy and lysis of adhesions were performed. Then, medial and lateral capsular release was practiced. To finish, an anterior interval release with intercondylar notch examination and debridement was performed. Bacteriological samples were systematically performed to exclude sepsis as a cause of stiffness.
Postoperative management
Patients underwent physiotherapy with no restrictions of flexion. Continuous passive motion with Kinetec Spectra Essential™ (Kinetec®) was performed for 20 h per each 24 h during immediate 7 days after surgery. No prophylactic thromboembolism anticoagulants were administered to reduce the risk of hematoma and adhesions reforming. Patients underwent clinical and radiological evaluation at 21 days, 45 days, 3 months, and 1 year postoperatively and then every year thereafter.
Evaluation of treatment effectiveness
Arthroscopic arthrolysis was considered effective if flexion was > 90° after 6 months and if there was no revision surgery.
Statistical analysis
Continuous variables were averaged and reported with standard deviation and extremes. The multinomial logistic regression model was used to investigate the relationship between stiffness and patient risk factors.
A P-value < 0.05 was considered statistically significant in each analysis. Statistical analyses were performed using XLstat (2015.1 version, Addinsoft, France).
Results
Stiffness
Firstly, stiffness incidence has been evaluated: 22 patients (9%) developed stiffness (Table 3).
Stiffness incidence and risk factors/ns: no significant, OR: odds ratio.
Risk factors (Table 3)
At a second time, risk factors to present stiffness have been evaluated.
Different risk factors studied were body mass index (BMI), age, mechanical versus robotic instrumentation, meniscectomy antecedent, preoperative flexion, taking anticoagulant, or not and taking antiplatelet agents or not and kind of implant. Results are summarized in Table 3.
Only one risk factor studied seemed to have a significant impact on stiffness: mechanical instrumentation (p = 0.005) with odds ratio, OR = 0.2. Thus, using robotic instrumentation reduces the risk of stiffness by > 5 times after UKA. Another interesting risk factor with an important OR was found: meniscectomy antecedent (OR = 2.4). The difference was no significant, but patients with meniscectomy antecedent have twice the risk to present stiffness.
Arthrolysis effectiveness
Finally, the effectiveness of arthroscopic treatment was evaluated. Before arthrolysis, the average knee flexion was 79° comparing to 121° after arthrolysis. The average increase in range of motion was 40° (53% improvement). Only 2 patients (9%) had a failure of arthrolysis and they were revised to a TKA.
Discussion
The most important finding of this study was that stiffness is an important complication after UKA, with 9% of the patients in this cohort presenting with stiffness after UKA. Arthroscopic debridement is an effective treatment with only 9% of patients still requiring revision to TKA after arthrolysis. Performing robotic-assisted UKA surgery significantly reduced the risk of stiffness by > 5 times (p = 0.005). Patients with meniscectomy antecedent present twice the risk to have stiffness after UKA.
After TKA, stiffness is a common complication. Multiple treatments are recommended: manipulation under anesthesia, arthroscopic arthrolysis, open surgery. Volchenko et al. [17] described a benefit to practicing arthroscopic lysis of adhesions associated under anesthesia (with 50% improvement) compared with manipulation under anesthesia alone on a cohort of 70 patients with stiffness after TKA. This improvement is similar to our study findings, in which there was a 53% improvement in knee flexion.
Regarding UKA, manipulation under anesthesia can be effective but may result in complications such as fracture, rupture of the extensor mechanism, or chondral damage [18]. Manipulation under anesthesia is only performed for stiffness after TKA, to avoid the risk of chondral damage in patients with UKA. However, performing a second invasive procedure may increase the risk of complications for patients, such as anesthesia complications, surgical complications, and periprosthetic sepsis compared to simple manipulation under anesthesia.
Hurst et al. [14] described arthroscopic evaluation after UKA for several complications. They found a stiffness rate of 12% after UKA, which is similar to our study. They concluded that arthroscopic evaluation after UKA is a safe method without any complication and effects on the implant survival rate. In our study, no patients had complications due to arthroscopy.
In our study, the robot seems to reduce the risk of stiffness. Several causes can explain this result.
Firstly, robotic-assisted surgery seems to improve implant positioning. Batailler et al. [2] had already shown that using robotic-assisted surgery increased the accuracy of implant positioning and decreased the revision rate. It is likely for those reasons that patients with robotic-assisted surgery have a lower rate of stiffness.
Indeed, Herry et al. [16] have shown better joint line restitution using robotic-assisted surgery during UKA. Simpson et al. [19] demonstrated that after UKA, mean strain on the proximal tibial cortex increased by 6, 13, and 18%, respectively, when tibial resection levels of 2, 4, and 6 mm were modeled, showing the importance to restore joint line-height to decrease pain and potentially stiffness after UKA. Robotic-assisted surgery appears to be superior by improving implant positioning and reducing complications after UKA.
The use of the robot allows better restitution of the physiological kinematics of the knee and this may explain the best post-operative follow-up and therefore the reduction of the risk of stiffness.
Then, several studies have shown a decrease in postoperative pain with the use of the robot [20, 21]. This may also explain the decrease in the rate of stiffness in patients operated with robotic.
Postoperative management is a very important point for us after stiffness treatment.
After primary TKA, continuous passive motion does not provide an additional benefit compared to traditional physiotherapy [22]. However, after surgery for stiffness, we believe that it assists patients in recovering self-confidence by allowing the patient to visualize the flexion improvement and help them to maintain the improvement over the first seven days. Leijtens et al. [23] have shown a high rate of bleeding complication after TKA and UKA for patients who are administered anticoagulant treatment. For this reason, no patients received anticoagulant treatment after arthroscopic debridement to decrease the risk of hematoma and stiffness. No patients had thrombo-embolism in our study.
It is important to note that there is very little literature reporting upon stiffness after UKA. There are numerous studies concerning stiffness after TKA, but not for UKA. This is surprising given that the rate of stiffness is around 9%, which is not much lower than a 12% stiffness rate after TKA. Stiffness after UKA is an important complication that deserves closer evaluation.
There are some limitations to this study that need to be acknowledged. By nature of the retrospective study design, some degree of bias could have been introduced, since patients were not randomized and indication bias for the use of robotic assistance surgery versus mechanical instrumentation may have occurred. Then, the short follow-up after arthroscopic treatment may overestimate the effectiveness of arthroscopic arthrolysis, however, the literature tells us that most stiffness occurs within the first two months.
Conclusions
Stiffness after UKA is an important complication with an incidence of 9% in this study. Arthroscopic arthrolysis is a safe and effective treatment with a range of motion improvement of > 50%. Robotic-assisted surgery significantly decreases the risk of postoperative stiffness.
Conflict of interest
Prof. Sébastien Lustig is a consultant for Medacta, Heraeus, Corin, Amplitude, Groupe Lépine, Depuy, Smith & Nephew, Stryker. Prof. Sébastien Lustig receives support from Corin and Amplitude. Prof. Sébastien Lustig is a board member of KSSTA, Maitrise Orthopédique. The other authors declare that they have no conflicts of interest.
Prof. Elvire Servien is a consultant for Corin and Smith & Nephew.
References
- Canetti R, Batailler C, Bankhead C, et al. (2018) Faster return to sport after robotic-assisted lateral unicompartmental knee arthroplasty: A comparative study. Arch Orthop Trauma Surg 138, 1765–1771. [CrossRef] [PubMed] [Google Scholar]
- Batailler C, White N, Ranaldi FM, et al. (2019) Improved implant position and lower revision rate with robotic-assisted unicompartmental knee arthroplasty. Knee Surg Sports Traumatol Arthrosc 27, 1232–1240. [CrossRef] [PubMed] [Google Scholar]
- Ode Q, Gaillard R, Batailler C, et al. (2018) Fewer complications after UKA than TKA in patients over 85 years of age: A case-control study. Orthop Traumatol Surg Res 104, 955–959. [CrossRef] [PubMed] [Google Scholar]
- Arirachakaran A, Choowit P, Putananon C, et al. (2015) Is unicompartmental knee arthroplasty (UKA) superior to total knee arthroplasty (TKA)? A systematic review and meta-analysis of randomized controlled trial. Eur J Orthop Surg Traumatol 25, 799–806. [CrossRef] [PubMed] [Google Scholar]
- Fabre-Aubrespy M, Ollivier M, Pesenti S, et al. (2016) Unicompartmental knee arthroplasty in patients older than 75 results in better clinical outcomes and similar survivorship compared to total knee arthroplasty. A Matched Controlled Study. J Arthroplasty 31, 2668–2671. [CrossRef] [PubMed] [Google Scholar]
- Lyons MC, MacDonald SJ, Somerville LE, et al. (2012) Unicompartmental versus total knee arthroplasty database analysis: Is there a winner? Clin Orthop Relat Res 470, 84–90. [CrossRef] [PubMed] [Google Scholar]
- Zhang Q-D, Guo W-S, Liu Z-H, et al. (2009) Meta-analysis of unicompartmental knee arthroplasty versus high tibial osteotomy in the treatment of unicompartmental knee osteoarthritis. Zhonghua Yi Xue Za Zhi 89, 2768–2772. [PubMed] [Google Scholar]
- Ho JC, Stitzlein RN, Green CJ, et al. (2016) Return to Sports Activity following UKA and TKA. J Knee Surg 29, 254–259. [PubMed] [Google Scholar]
- Rodríguez-Merchán EC, Gómez-Cardero P (2018) Unicompartmental knee arthroplasty: Current indications, technical issues and results. EFORT Open Rev 3, 363–373. [CrossRef] [PubMed] [Google Scholar]
- Mohammad HR, Strickland L, Hamilton TW, Murray DW (2018) Long-term outcomes of over 8,000 medial Oxford Phase 3 Unicompartmental Knees-a systematic review. Acta Orthop 89, 101–107. [CrossRef] [PubMed] [Google Scholar]
- Kim J, Nelson CL, Lotke PA (2004) Stiffness after total knee arthroplasty. Prevalence of the complication and outcomes of revision. J Bone Joint Surg Am 86, 1479–1484. [CrossRef] [PubMed] [Google Scholar]
- Cheuy VA, Foran JRH, Paxton RJ, et al. (2017) Arthrofibrosis Associated With Total Knee Arthroplasty. J Arthroplasty 32, 2604–2611. [CrossRef] [PubMed] [Google Scholar]
- Kim KT, Lee S, Lee JI, Kim JW (2016) Analysis and Treatment of Complications after Unicompartmental Knee Arthroplasty. Knee Surg Relat Res 28, 46–54. [CrossRef] [PubMed] [Google Scholar]
- Hurst JM, Ranieri R, Berend KR, et al. (2018) Outcomes after arthroscopic evaluation of patients with painful medial unicompartmental knee arthroplasty. The Journal of Arthroplasty 33, 3268–3272. [CrossRef] [PubMed] [Google Scholar]
- Lonner JH, Smith JR, Picard F, et al. (2015) High degree of accuracy of a novel image-free handheld robot for unicondylar knee arthroplasty in a cadaveric study. Clin Orthop Relat Res 473, 206–212. [CrossRef] [PubMed] [Google Scholar]
- Herry Y, Batailler C, Lording T, et al. (2017) Improved joint-line restitution in unicompartmental knee arthroplasty using a robotic-assisted surgical technique. Int Orthop 41, 2265–2271. [CrossRef] [PubMed] [Google Scholar]
- Volchenko E, Schwarzman G, Robinson M, et al. (2019) Arthroscopic Lysis of Adhesions With Manipulation Under Anesthesia Versus Manipulation Alone in the Treatment of Arthrofibrosis After TKA: A Matched Cohort Study. Orthopedics 42, 163–167. [CrossRef] [PubMed] [Google Scholar]
- Kukreja M, Kang J, Curry EJ, Li X (2019) Arthroscopic lysis of adhesions and anterior interval release with manipulation under anesthesia for severe post-traumatic knee stiffness: A simple and reproducible step-by-step guide. Arthroscopy Tech 8, e429–e435. [Google Scholar]
- Simpson DJ, Price AJ, Gulati A, et al. (2009) Elevated proximal tibial strains following unicompartmental knee replacement–a possible cause of pain. Med Eng Phys 31, 752–757. [CrossRef] [PubMed] [Google Scholar]
- Mergenthaler G, Batailler C, Lording T, et al. (2021). Is robotic-assisted unicompartmental knee arthroplasty a safe procedure? A case control study. Knee Surg Sports Traumatol Arthrosc 9(3), 931–938. [Google Scholar]
- Negrín R, Duboy J, Iñiguez M, et al. (2021) Robotic-assisted vs conventional surgery in medial unicompartmental knee arthroplasty: A clinical and radiological study. Knee Surg Relat Res 33, 5. [CrossRef] [PubMed] [Google Scholar]
- Herbold JA, Bonistall K, Blackburn M, et al. (2014) Randomized controlled trial of the effectiveness of continuous passive motion after total knee replacement. Arch Phys Med Rehabil 95, 1240–1245. [CrossRef] [PubMed] [Google Scholar]
- Leijtens B, Kremers van de Hei K, Jansen J, Koëter S (2014) High complication rate after total knee and hip replacement due to perioperative bridging of anticoagulant therapy based on the 2012 ACCP guideline. Arch Orthop Trauma Surg 134, 1335–1341. [CrossRef] [PubMed] [Google Scholar]
Cite this article as: Fournier G, Gaillard R, Swan J, Batailler C, Lustig S & Servien E (2021) Stiffness after unicompartmental knee arthroplasty: Risk factors and arthroscopic treatment. SICOT-J 7, 35
All Tables
Final study population characteristics SD standard deviation, Min minimum, Max maximum.
All Figures
Figure 1 Flowchart. |
|
In the text |
Figure 2 Medial HLS Uni Evolution™ UKA (AP view and profile). |
|
In the text |
Figure 3 Medial Journey™ UKA, (AP view and profile). |
|
In the text |
Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.
Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.
Initial download of the metrics may take a while.