Open Access
Volume 7, 2021
Article Number 53
Number of page(s) 5
Section Lower Limb
Published online 28 October 2021
  1. Kaye JA, Jick H (2004) Epidemiology of lower limb fractures in general practice in the United Kingdom. Inj Prev 10, 368–374. [CrossRef] [PubMed] [Google Scholar]
  2. Lawrence VA, Silverstein JH, Cornell JE, Pederson T, Noveck H, Carson JL (2003) Higher Hb level is associated with better early functional recovery after hip fracture repair. Transfusion 43, 1717–1722. [CrossRef] [PubMed] [Google Scholar]
  3. Foss NB, Kristensen MT, Kehlet H (2008) Anaemia impedes functional mobility after hip fracture surgery. Age Ageing 37, 173–178. [CrossRef] [PubMed] [Google Scholar]
  4. Mannucci PM, Levi M (2007) Prevention and treatment of major blood loss. N Engl J Med 356, 2301–2311. [CrossRef] [PubMed] [Google Scholar]
  5. Calapai G, Gangemi S, Mannucci C, et al. (2015) Systematic review of tranexamic acid adverse reactions. J Pharmacovigilance 3, 171. [CrossRef] [Google Scholar]
  6. Sahu S, Hemlata VA (2014) Adverse events related to blood transfusion. Indian J Anaesth 58, 543–551. [CrossRef] [PubMed] [Google Scholar]
  7. Gandhi R, Evans HM, Mahomed SR, Mahomed NN (2013) Tranexamic acid and the reduction of blood loss in total knee and hip arthroplasty: a meta-analysis. BMC Res Notes 6, 1–14. [CrossRef] [PubMed] [Google Scholar]
  8. Zufferey PJ, Miquet M, Quenet S, et al. (2010) Tranexamic acid in hip fracture surgery: a randomized controlled trial. Br J Anaesth 104, 23–30. [CrossRef] [PubMed] [Google Scholar]
  9. Amin MS, Habib MK, Rehman AU (2020) Comparison of blood loss between intra-articular and intra-venous administration of tranexamic acid in primary total knee arthroplasty. SICOT-J 6, 20. [CrossRef] [EDP Sciences] [PubMed] [Google Scholar]
  10. Shakur H, Roberts I, Bautista R, et al. (2010) Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial. Lancet 376, 23–32. [Google Scholar]
  11. Ker K, Edwards P, Perel P, et al. (2012) Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis. BMJ 344, e3054. [CrossRef] [PubMed] [Google Scholar]
  12. Napolitano LM, Cohen MJ, Cotton BA, et al. (2013) Tranexamic acid in trauma: how should we use it? J Trauma Acute Care Surg 74, 1575–1586. [CrossRef] [PubMed] [Google Scholar]
  13. Pusateri AE, Weiskopf RB, Bebarta V, et al. (2013) Tranexamic acid and trauma: current status and knowledge gaps with recommended research priorities. Shock 39, 121–126. [CrossRef] [PubMed] [Google Scholar]
  14. Wells PS, Anderson DR, Bormanis J, et al. (1997) Value of assessment of pretest probability of deep-vein thrombosis in clinical management. Lancet 350, 1795–1798. [CrossRef] [PubMed] [Google Scholar]
  15. Vijay BS, Bedi V, Mitra S, Das B (2013) Role of tranexamic acid in reducing postoperative blood loss and transfusion requirement in patients undergoing hip and femoral surgeries. Saudi J Anaesth 7, 29–32. [CrossRef] [PubMed] [Google Scholar]
  16. Cohen MJ (2012) Towards hemostatic resuscitation: the changing understanding of acute traumatic biology, massive bleeding, and damage-control resuscitation. Surg Clin North Am 92, 877–891. [CrossRef] [PubMed] [Google Scholar]
  17. Wu G, Mazzitelli BA, Quek AJ, et al. (2019) Tranexamic acid is an active site inhibitor of urokinase plasminogen activator. Blood Adv 3, 729–733. [CrossRef] [PubMed] [Google Scholar]
  18. Ramirez RJ, Spinella PC, Bochicchio GV (2017) Tranexamic acid update in trauma. Crit Care Clin 33, 85–99. [CrossRef] [PubMed] [Google Scholar]
  19. Poeran J, Rasul R, Suzuki S, et al. (2014) Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety. BMJ 349, g4829. [CrossRef] [PubMed] [Google Scholar]
  20. Gausden EB, Garner MR, Warner SJ, et al. (2016) Tranexamic acid in hip fracture patients: a protocol for a randomised, placebo controlled trial on the efficacy of tranexamic acid in reducing blood loss in hip fracture patients. BMJ Open 6, e010676. [CrossRef] [PubMed] [Google Scholar]
  21. Zhang P, Bai JZ, He J, Liang Y, Chen P, Wang JC (2018) A systematic review of tranexamic acid usage in patients undergoing femoral fracture surgery. Clin Interv Aging 13, 1579–1591. [CrossRef] [Google Scholar]
  22. Lanoiselée J, Zufferey PJ, Ollier E, Hodin S, Delavenne X (2018) Perioperative Tranexamic acid in hip arthroplasty (PORTO) study investigators. Is tranexamic acid exposure related to blood loss in hip arthroplasty? A pharmacokinetic-pharmacodynamic study. Br J Clin Pharmacol 84, 310–319. [CrossRef] [PubMed] [Google Scholar]
  23. Robertson J, Koyfman OHA (2015) Does tranexamic acid improve outcomes in patients undergoing urgent or emergency surgery? Ann Emerg Med 65, 445–446. [CrossRef] [PubMed] [Google Scholar]
  24. Sadeghi M, Mehr-Aein A (2007) Does a single bolus dose of tranexamic acid reduce blood loss and transfusion requirements during hip fracture surgery? A prospective randomized double blind study in 67 patients. Acta Med Iran 45, 437–442. [Google Scholar]
  25. Farrow LS, Smith TO, Ashcroft GP, Myint PA (2016) A systematic review of tranexamic acid in hip fracture surgery. Br J Clin Pharmacol 82, 1458–1470. [CrossRef] [PubMed] [Google Scholar]
  26. Sassoon A, Nam D, Jackups R, Johnson SR, Nunley RM, Barrack RL (2016) Tranexamic acid. Bone Jt J 98(2), 173–178. [CrossRef] [PubMed] [Google Scholar]
  27. Howard DC, Skeith A, Caughey AB (2019) Cost-effectiveness of prophylactic tranexamic acid use in women at increased risk of postpartum hemorrhage. Obstet Gynecol 133, 26S. [CrossRef] [Google Scholar]
  28. Fischer PE, Bulger EM, Perina DG, et al. (2016) Guidance document for the prehospital use of tranexamic acid in injured patients. Prehosp Emerg Care 20, 557–559. [CrossRef] [PubMed] [Google Scholar]

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